Cecilie Delphin Amdal

  • Group leader, consultant; MD, PhD
 

Publications 2024

Huynh TM, Falk RS, Hellebust TP, Dale E, Astrup GL, Hjermstad MJ, Malinen E, Bjordal K, Kiserud CE, Herlofson BB, Nome R, Amdal CD (2024)
Chronic fatigue in long-term survivors of head and neck cancer treated with radiotherapy
Radiother Oncol, 195, 110231 (in press)
DOI 10.1016/j.radonc.2024.110231, PubMed 38518958

Taylor KJ, Amdal CD, Bjordal K, Astrup GL, Herlofson BB, Duprez F, Gama RR, Jacinto A, Hammerlid E, Scricciolo M, Jansen F, Verdonck-de Leeuw IM, Fanetti G, Guntinas-Lichius O, Inhestern J, Dragan T, Fabian A, Boehm A, Wöhner U, Kiyota N, Krüger M, Bonomo P, Pinto M, Nuyts S, Silva JC et al. (2024)
Long-term health-related quality of life in head and neck cancer survivors: A large multinational study
Int J Cancer, 154 (10), 1772-1785
DOI 10.1002/ijc.34861, PubMed 38312044

Publications 2023

Amdal CD, Moan JM, Dale E, Falk RS, Johansen S, Bjordal K (2023)
Impact of hyperfractionated re-irradiation on quality of life in patients with recurrent or second primary head and neck cancer, a prospective single institutional study
Clin Transl Radiat Oncol, 42, 100654
DOI 10.1016/j.ctro.2023.100654, PubMed 37415638

Huynh TM, Dale E, Falk RS, Hellebust TP, Astrup GL, Malinen E, Edin NFJ, Bjordal K, Herlofson BB, Kiserud CE, Helland Å, Amdal CD (2023)
Radiation-induced long-term dysphagia in survivors of head and neck cancer and association with dose-volume parameters
Radiother Oncol, 190, 110044
DOI 10.1016/j.radonc.2023.110044, PubMed 38061420

Liu L, Choi J, Musoro JZ, Sauerbrei W, Amdal CD, Alanya A, Barbachano Y, Cappelleri JC, Falk RS, Fiero MH, Regnault A, Reijneveld JC, Sandin R, Thomassen D, Roychoudhury S, Goetghebeur E, le Cessie S, SISAQOL-IMI Work Package 3 (2023)
Single-arm studies involving patient-reported outcome data in oncology: a literature review on current practice
Lancet Oncol, 24 (5), e197-e206
DOI 10.1016/S1470-2045(23)00110-9, PubMed 37142381

Pe M, Alanya A, Falk RS, Amdal CD, Bjordal K, Chang J, Cislo P, Coens C, Dirven L, Speck RM, Fitzgerald K, Galinsky J, Giesinger JM, Holzner B, Le Cessie S, O'Connor D, Oliver K, Pawar V, Quinten C, Schlichting M, Ren J, Roychoudhury S, Taphoorn MJB, Velikova G, Wintner LM et al. (2023)
Setting International Standards in Analyzing Patient-Reported Outcomes and Quality of Life Endpoints in Cancer Clinical Trials-Innovative Medicines Initiative (SISAQOL-IMI): stakeholder views, objectives, and procedures
Lancet Oncol, 24 (6), e270-e283
DOI 10.1016/S1470-2045(23)00157-2, PubMed 37269858

Taylor KJ, Amdal CD, Bjordal K, Astrup GL, Herlofson BB, Duprez F, Gama RR, Jacinto A, Hammerlid E, Scricciolo M, Jansen F, Verdonck-de Leeuw IM, Fanetti G, Guntinas-Lichius O, Inhestern J, Dragan T, Fabian A, Boehm A, Wöhner U, Kiyota N, Krüger M, Bonomo P, Pinto M, Nuyts S, Silva JC et al. (2023)
Serious Long-Term Effects of Head and Neck Cancer from the Survivors' Point of View
Healthcare (Basel), 11 (6)
DOI 10.3390/healthcare11060906, PubMed 36981562

Trøseid M, Arribas JR, Assoumou L, Holten AR, Poissy J, Terzić V, Mazzaferri F, Baño JR, Eustace J, Hites M, Joannidis M, Paiva JA, Reuter J, Püntmann I, Patrick-Brown TDJH, Westerheim E, Nezvalova-Henriksen K, Beniguel L, Dahl TB, Bouscambert M, Halanova M, Péterfi Z, Tsiodras S, Rezek M, Briel M et al. (2023)
Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomised, double-blind, placebo-controlled phase 3 trial
Crit Care, 27 (1), 9
DOI 10.1186/s13054-022-04205-8, PubMed 36627655

Publications 2022

Amdal CD, Falk RS, Singer S, Pe M, Piccinin C, Bottomley A, Appiah LT, Arraras JI, Bayer O, Buanes EA, Darlington AS, Arbanas GD, Hofsø K, Holzner B, Sahlstrand-Johnson P, Kuliś D, Parmar G, Rmeileh NMEA, Schranz M, Sodergren S, Bjordal K (2022)
A multicenter international prospective study of the validity and reliability of a COVID-19-specific health-related quality of life questionnaire
Qual Life Res, 32 (2), 447-459
DOI 10.1007/s11136-022-03272-2, PubMed 36273365

Amdal CD, Taylor K, Kuliś D, Falk RS, Bottomley A, Arraras JI, Barte JH, Darlington AS, Hofsø K, Holzner B, Jørgensen NMH, Mariano MP, Pe M, Piccinin C, Riccetti N, Schranz M, Wheelwright S, Bjordal K (2022)
Health-related quality of life in patients with COVID-19; international development of a patient-reported outcome measure
J Patient Rep Outcomes, 6 (1), 26
DOI 10.1186/s41687-022-00434-1, PubMed 35348945

Huynh TTM, Aass HCD, Falk RS, Astrup GL, Helland Å, Bjøro T, Bjordal K, Dale E, Hellebust TP, Herlofson BB, Malinen E, Kiserud CE, Osnes T, Amdal CD (2022)
Associations between patient-reported late effects and systemic cytokines in long-term survivors of head and neck cancer treated with radiotherapy
J Cancer Surviv, 17 (4), 1082-1093
DOI 10.1007/s11764-022-01273-1, PubMed 36350483

Hynne H, Aqrawi LA, Jensen JL, Thiede B, Palm Ø, Amdal CD, Westgaard KL, Herlofson BB, Utheim TP, Galtung HK (2022)
Proteomic Profiling of Saliva and Tears in Radiated Head and Neck Cancer Patients as Compared to Primary Sjögren's Syndrome Patients
Int J Mol Sci, 23 (7)
DOI 10.3390/ijms23073714, PubMed 35409074

Ivanova A, Rodríguez-Cano R, Kvalem IL, Harcourt D, Kiserud CE, Amdal CD (2022)
Body image concerns in long-term head and neck cancer survivors: prevalence and role of clinical factors and patient-reported late effects
J Cancer Surviv, 17 (2), 526-534
DOI 10.1007/s11764-022-01311-y, PubMed 36509859

Publications 2021

Amdal CD, Pe M, Falk RS, Piccinin C, Bottomley A, Arraras JI, Darlington AS, Hofsø K, Holzner B, Jørgensen NMH, Kulis D, Rimehaug SA, Singer S, Taylor K, Wheelwright S, Bjordal K (2021)
Health-related quality of life issues, including symptoms, in patients with active COVID-19 or post COVID-19; a systematic literature review
Qual Life Res, 30 (12), 3367-3381
DOI 10.1007/s11136-021-02908-z, PubMed 34146226

Astrup GL, Rohde G, Rimehaug SA, Andersen MH, Bernklev T, Bjordal K, Falk RS, Jørgensen NMH, Stavem K, Tollisen A, Amdal CD, (2021)
Comparing the use of patient-reported outcomes in clinical studies in Europe in 2008 and 2018: a literature review
Qual Life Res, 31 (3), 659-669
DOI 10.1007/s11136-021-02946-7, PubMed 34350566

Chen X, Badian RA, Hynne H, Amdal CD, Herlofson BB, Utheim ØA, Westgaard KL, Fineide F, Jensen JL, Utheim TP (2021)
Alterations in meibomian glands in patients treated with intensity-modulated radiotherapy for head and neck cancer
Sci Rep, 11 (1), 22419
DOI 10.1038/s41598-021-01844-9, PubMed 34789830

Singer S, Hammerlid E, Tomaszewska IM, Amdal CD, Bjordal K, Herlofson BB, Santos M, Silva JC, Mehanna H, Fullerton A, Brannan C, Gonzalez LF, Inhestern J, Pinto M, Arraras JI, Yarom N, Bonomo P, Baumann I, Galalae R, Nicolatou-Galitis O, Kiyota N, Raber-Durlacher J, Salem D, Fabian A, Boehm A et al. (2021)
Methodological approach for determining the Minimal Important Difference and Minimal Important Change scores for the European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module (EORTC QLQ-HN43) exemplified by the Swallowing scale
Qual Life Res, 31 (3), 841-853
DOI 10.1007/s11136-021-02939-6, PubMed 34272632

Westgaard KL, Hynne H, Amdal CD, Young A, Singh PB, Chen X, Rykke M, Hove LH, Aqrawi LA, Utheim TP, Herlofson BB, Jensen JL (2021)
Oral and ocular late effects in head and neck cancer patients treated with radiotherapy
Sci Rep, 11 (1), 4026
DOI 10.1038/s41598-021-83635-w, PubMed 33597629

Publications 2020

Aqrawi LA, Chen X, Hynne H, Amdal C, Reppe S, Aass HCD, Rykke M, Hove LH, Young A, Herlofson BB, Westgaard KL, Utheim TP, Galtung HK, Jensen JL (2020)
Cytokines Explored in Saliva and Tears from Radiated Cancer Patients Correlate with Clinical Manifestations, Influencing Important Immunoregulatory Cellular Pathways
Cells, 9 (9)
DOI 10.3390/cells9092050, PubMed 32911805

Hauge T, Amdal CD, Falk RS, Johannessen HO, Johnson E (2020)
Long-term outcome in patients operated with hybrid esophagectomy for esophageal cancer - a cohort study
Acta Oncol, 59 (7), 859-865
DOI 10.1080/0284186X.2020.1750694, PubMed 32324079

Publications 2019

Moan JM, Amdal CD, Malinen E, Svestad JG, Bogsrud TV, Dale E (2019)
The prognostic role of 18F-fluorodeoxyglucose PET in head and neck cancer depends on HPV status
Radiother Oncol, 140, 54-61
DOI 10.1016/j.radonc.2019.05.019, PubMed 31177043

Singer S, Amdal CD, Hammerlid E, Tomaszewska IM, Castro Silva J, Mehanna H, Santos M, Inhestern J, Brannan C, Yarom N, Fullerton A, Pinto M, Arraras JI, Kiyota N, Bonomo P, Sherman AC, Baumann I, Galalae R, Fernandez Gonzalez L, Nicolatou-Galitis O, Abdel-Hafeez Z, Raber-Durlacher J, Schmalz C, Zotti P, Boehm A et al. (2019)
International validation of the revised European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module, the EORTC QLQ-HN43: Phase IV
Head Neck, 41 (6), 1725-1737
DOI 10.1002/hed.25609, PubMed 30636188

Publications 2018

Enden T, Bernklev T, Jelsness-Jorgensen LP, Amdal CD (2018)
Patients know their own health best
Tidsskr. Nor. Laegeforen., 138 (8), 716-718

Enden T, Bernklev T, Jelsness-Jørgensen LP, Amdal CD (2018)
[Patients know their own health best]
Tidsskr Nor Laegeforen, 138 (8)
DOI 10.4045/tidsskr.17.1054, PubMed 29737772

Skjøtskift T, Evensen ME, Furre T, Moan JM, Amdal CD, Bogsrud TV, Malinen E, Dale E (2018)
Dose painting for re-irradiation of head and neck cancer
Acta Oncol, 57 (12), 1693-1699
DOI 10.1080/0284186X.2018.1512753, PubMed 30280623

Publications 2017

Amdal CD, Jacobsen AB, Falk RS, Johnson E, Os SS, Warloe T, Bjordal K (2017)
Improved treatment decisions in patients with esophageal cancer
Acta Oncol, 56 (10), 1286-1294
DOI 10.1080/0284186X.2017.1346379, PubMed 28686501

Johansen S, Norman MH, Dale E, Amdal CD, Furre T, Malinen E, Evensen JF (2017)
Patterns of local-regional recurrence after conformal and intensity-modulated radiotherapy for head and neck cancer
Radiat Oncol, 12 (1), 87
DOI 10.1186/s13014-017-0829-5, PubMed 28545588

Publications 2014

Amdal CD, Bjordal K (2014)
Are surrogate endpoints useful in clinical studies?
Tidsskr Nor Laegeforen, 134 (11), 1128-9
DOI 10.4045/tidsskr.14.0411, PubMed 24939776

Publications 2013

Amdal CD, Jacobsen AB, Sandstad B, Warloe T, Bjordal K (2013)
Palliative brachytherapy with or without primary stent placement in patients with oesophageal cancer, a randomised phase III trial
Radiother Oncol, 107 (3), 428-33
DOI 10.1016/j.radonc.2013.04.008, PubMed 23647761

Publications 2012

Amdal CD, Jacobsen AB, Guren MG, Bjordal K (2012)
Patient-reported outcomes evaluating palliative radiotherapy and chemotherapy in patients with oesophageal cancer: a systematic review
Acta Oncol, 52 (4), 679-90
DOI 10.3109/0284186X.2012.731521, PubMed 23190360

Publications 2011

Amdal CD, Jacobsen AB, Tausjø JE, Wiig JN, Warloe T, Sandstad B, Bjordal K (2011)
Palliative interventions and prognosis in patients with advanced esophageal cancer
Dis Esophagus, 24 (7), 502-9
DOI 10.1111/j.1442-2050.2010.01174.x, PubMed 21309923

Publications 2010

Amdal CD, Jacobsen AB, Tausjø JE, Wiig JN, Warloe T, Karlsen KO, Sandstad B, Bjordal K (2010)
Radical treatment for oesophageal cancer patients unfit for surgery and chemotherapy. A 10-year experience from the Norwegian Radium Hospital
Acta Oncol, 49 (2), 209-18
DOI 10.3109/02841860903246573, PubMed 19929566

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